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Multiple endocrine neoplastic-associated thymic carcinoid tumour in close relatives: octreotide scan as a new diagnostic and follow-up modality. Two case reports.

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Multiple endocrine neoplastic-associated thymic carcinoid tumour in close relatives: octreotide scan as a new diagnostic and follow-up modality. Two case reports.

Auteurs : RBID : pubmed:10093860

English descriptors

Abstract

Thymic carcinoid tumours constitute less than 1% of all carcinoids, and differ markedly from true thymomas in natural history, morphology, prognosis and therapeutic options. New clinical and diagnostic modalities are described in two brothers with thymic carcinoid associated with multiple endocrine neoplasia syndrome. Octreotide scintigraphy proved useful for diagnosis and follow-up, and somatostatin receptor positivity may provide new prospects for treatment of non-resectable or recurrent tumour.

PubMed: 10093860

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Le document en format XML

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<title xml:lang="en">Multiple endocrine neoplastic-associated thymic carcinoid tumour in close relatives: octreotide scan as a new diagnostic and follow-up modality. Two case reports.</title>
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<name sortKey="Satta, J" uniqKey="Satta J">J Satta</name>
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<nlm:affiliation>Department of Surgery, University of Oulu, Finland.</nlm:affiliation>
<country xml:lang="fr">Finlande</country>
<wicri:regionArea>Department of Surgery, University of Oulu</wicri:regionArea>
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<name sortKey="Ahonen, A" uniqKey="Ahonen A">A Ahonen</name>
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<name sortKey="Parkkila, S" uniqKey="Parkkila S">S Parkkila</name>
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<name sortKey="Leinonen, L" uniqKey="Leinonen L">L Leinonen</name>
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<name sortKey="Apaja Sarkkinen, M" uniqKey="Apaja Sarkkinen M">M Apaja-Sarkkinen</name>
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<author>
<name sortKey="Lepoj Rvi, M" uniqKey="Lepoj Rvi M">M Lepojärvi</name>
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<author>
<name sortKey="Juvonen, T" uniqKey="Juvonen T">T Juvonen</name>
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<term>Carcinoid Tumor (radiography)</term>
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<term>Carcinoid Tumor (surgery)</term>
<term>Hormones (diagnostic use)</term>
<term>Humans</term>
<term>Indium Radioisotopes (diagnostic use)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Multiple Endocrine Neoplasia Type 1 (genetics)</term>
<term>Multiple Endocrine Neoplasia Type 1 (radiography)</term>
<term>Multiple Endocrine Neoplasia Type 1 (radionuclide imaging)</term>
<term>Multiple Endocrine Neoplasia Type 1 (surgery)</term>
<term>Octreotide (diagnostic use)</term>
<term>Pentetic Acid (diagnostic use)</term>
<term>Receptors, Somatostatin</term>
<term>Somatostatin (analogs & derivatives)</term>
<term>Somatostatin (diagnostic use)</term>
<term>Thymus Gland (radiography)</term>
<term>Thymus Gland (radionuclide imaging)</term>
<term>Thymus Neoplasms (genetics)</term>
<term>Thymus Neoplasms (radiography)</term>
<term>Thymus Neoplasms (radionuclide imaging)</term>
<term>Thymus Neoplasms (surgery)</term>
<term>Tomography, X-Ray Computed</term>
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<term>Somatostatin</term>
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<term>Hormones</term>
<term>Indium Radioisotopes</term>
<term>Octreotide</term>
<term>Pentetic Acid</term>
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<term>Carcinoid Tumor</term>
<term>Multiple Endocrine Neoplasia Type 1</term>
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<term>Multiple Endocrine Neoplasia Type 1</term>
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<div type="abstract" xml:lang="en">Thymic carcinoid tumours constitute less than 1% of all carcinoids, and differ markedly from true thymomas in natural history, morphology, prognosis and therapeutic options. New clinical and diagnostic modalities are described in two brothers with thymic carcinoid associated with multiple endocrine neoplasia syndrome. Octreotide scintigraphy proved useful for diagnosis and follow-up, and somatostatin receptor positivity may provide new prospects for treatment of non-resectable or recurrent tumour.</div>
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